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Ancestral Sequence Reconstruction$
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David A Liberles

Print publication date: 2007

Print ISBN-13: 9780199299188

Published to Oxford Scholarship Online: September 2008

DOI: 10.1093/acprof:oso/9780199299188.001.0001

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Dealing with model uncertainty in reconstructing ancestral proteins in the laboratory: examples from archosaur visual pigments and coralfluorescent proteins

Dealing with model uncertainty in reconstructing ancestral proteins in the laboratory: examples from archosaur visual pigments and coralfluorescent proteins

Chapter:
(p.164) CHAPTER 15 Dealing with model uncertainty in reconstructing ancestral proteins in the laboratory: examples from archosaur visual pigments and coralfluorescent proteins
Source:
Ancestral Sequence Reconstruction
Author(s):

Belinda S.W. Chang

Mikhail V. Matz

Steven F. Field

Johannes Müller

Ilke van Hazel

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199299188.003.0015

This chapter discusses efficient experimental strategies to explore variation in ancestral sequence reconstructions. The experimental strategies are illustrated with two examples, ancestral rhodopsins in archosaurs and green fluorescent protein (GFP)-like proteins in corals.

Keywords:   ancestral sequence reconstruction, ancestral rhodopsins, archosaurs, green fluorescent protein, corals, gene synthesis

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