Jump to ContentJump to Main Navigation
Parsimony, Phylogeny, and Genomics$
Users without a subscription are not able to see the full content.

Victor A. Albert

Print publication date: 2006

Print ISBN-13: 9780199297306

Published to Oxford Scholarship Online: September 2007

DOI: 10.1093/acprof:oso/9780199297306.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2018. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a monograph in OSO for personal use (for details see www.oxfordscholarship.com/page/privacy-policy).date: 13 November 2018

Dollo parsimony and the reconstruction of genome evolution

Dollo parsimony and the reconstruction of genome evolution

Chapter:
(p.190) Chapter 11 Dollo parsimony and the reconstruction of genome evolution
Source:
Parsimony, Phylogeny, and Genomics
Author(s):

Igor B. Rogozin

Yuri I. Wolf

Vladimir N. Babenko

Eugene V. Koonin

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199297306.003.0011

The Dollo parsimony method is based on the assumption that a complex character that has been lost during evolution of a particular lineage cannot be regained. When applicable, this principle leads to a substantial simplification of evolutionary analysis and provides for unambiguous reconstruction of evolutionary scenarios, which may not be attainable with other methods. In this chapter, applications of Dollo parsimony are described for the quantitative analysis of the dynamics of genome evolution. Dollo parsimony is the method of choice for reconstructing evolution of the gene repertoire of eukaryotic organisms because although multiple, independent losses of a gene in different lineages are common, multiple gains of the same gene are improbable. This contrasts with the situation in prokaryotes where the widespread occurrence of horizontal gene transfer makes multiple gains possible, thereby invalidating the Dollo principle. The chapter applies Dollo parsimony to reconstruct the scenario of evolution for the genomes of crown-group eukaryotes by assigning the loss of genes and emergence of new genes to the branches of the phylogenetic tree, and delineate the minimal gene sets for various ancestral forms. A similar analysis, with rather unexpected results, was performed to infer gain versus loss of introns in conserved eukaryotic genes. The applicability of the Dollo principle for these and other problems in evolutionary genomics is discussed.

Keywords:   complex character, gene loss, gene gain, horizontal gene transfer, eukaryotes, prokaryotes, minimal gene sets, ancestral states, introns

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .