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A Decade of HAART
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A Decade of HAART: The Development and Global Impact of Highly Active Antiretroviral Therapy

José M. Zuniga, Alan Whiteside, Amin Ghaziani, and John G. Bartlett

Abstract

Highly active antiretroviral therapy (HAART) is a therapeutic intervention developed by clinicians and researchers in order to fight the HIV pandemic. It has contributed to a significant reduction in AIDS-related mortality and allowed many previously bed-ridden patients to live healthier, more productive lives. Until the advent of HAART in 1996, a diagnosis of HIV infection was considered a death sentence. A decade later, the disease has been transformed into a serious, yet potentially manageable, medical condition for thousands of people living with HIV/AIDS in the developed world — almost ov ... More

Keywords: HAART, HIV, AIDS, highly active antiretroviral therapy, HIV treatment

Bibliographic Information

Print publication date: 2008 Print ISBN-13: 9780199225859
Published to Oxford Scholarship Online: September 2009 DOI:10.1093/acprof:oso/9780199225859.001.0001

Authors

Affiliations are at time of print publication.

José M. Zuniga, editor
President/CEO, International Association of Physicians in AIDS Care, Chicago, USA

Alan Whiteside, editor
Director, Health and Economics and HIV/AIDS Research Division (HEARD), University of KwaZulu-Natal, Durban, South Africa

Amin Ghaziani, editor
Cotsen Postdoctoral Fellow, Society of Fellows, Princeton University, USA

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Contents

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Part 1 A decade of HAART: trials, tribulations and successes

Chapter 1 Introduction

José M. Zuniga*, Alan Whiteside, Amin Ghaziani and John G. Bartlett

Chapter 2 A world ravaged by a disease without HAART

José M. Zuniga* and Amin Ghaziani

Chapter 4 The outcome and impact of 10 years of HAART

Eduard J. Beck* and Rochelle P. Walensky

Chapter 5 HAART in HIV-infected children: one decade later

Arry Dieudonne*, James A. McIntyre, Federica Fregonese, Carlo Giaquinto and James M. Oleske

Part 2 HAART in high human development countries

Chapter 6 Country review: Australia

Kathleen Glenday, Kathy Petoumenos*, Matthew G. Law and David A. Cooper

Chapter 8 Country review: Germany

Eva Wolf* and Hans Jaeger

Chapter 11 US Cohorts review: The HIV Outpatient Study (HOPS) and the Multicenter AIDS Cohort Study (MACS)

Frank J. Palella, Jr*, Anne C. Moorman, John T. Brooks (HOPS)l; John Phair*, Lisa Jacobson, Roger Detels, Joseph Margolick and Charles Rinaldo (MACS)

Chapter 14 The Swiss HIV Cohort Study (SHCS)

Huldrych F. Günthard and Bernard Hirschel*

Part 3 HAART in medium human development countries

Chapter 16 Country review: Brazil

Celso Ferreira Ramos-Filho* and Cledy Eliana dos Santos

Chapter 17 Country review: China

Zhang Fu-Jie*, Ray Y. Chen, Selina N. Lo and Ma Ye

Chapter 18 Country review: South Africa

Robin Wood* and Des Martin

Chapter 19 Country review: Thailand

Praphan Phanuphak*, Sanchai Chasombat and Jintanat Ananworanich

Chapter 20 Cohort studies in Brazil: Projeto Praça Onze

Mauro Schechter* and Suely Hiromi Tuboi

Part 4 HAART in low human development countries

Chapter 22 Country review: Haiti

Serena Koenig*, Julia Carney, Peter Bendix and Jean William Pape

Chapter 23 Country review: Malawi

Erik J. Schouten*, Simon D. Makombe, Anthony D. Harries and Kelita Kamoto

Chapter 25 Country review: Zambia

Moses Sinkala and Benjamin H. Chi*

Part 5 Future challenges in the next decade of HAART

Chapter 26 The clinical challenges of lifetime HAART

Roger Paredes*, Renslow Sherer and Bonaventura Clotet

Chapter 28 Redefining HIV/AIDS care delivery in the face of human resource scarcity

Mario Roberto Dal Poz*, Norbert Dreesch and Dingie van Rensburg

End Matter