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Aging of the GenomeThe dual role of DNA in life and death$
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Jan Vijg

Print publication date: 2007

Print ISBN-13: 9780198569237

Published to Oxford Scholarship Online: April 2010

DOI: 10.1093/acprof:oso/9780198569237.001.0001

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Introduction: the coming of age of the genome

Introduction: the coming of age of the genome

Chapter:
(p.1) 1 Introduction: the coming of age of the genome
Source:
Aging of the Genome
Author(s):

Jan Vijg

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198569237.003.0001

This chapter sketches the major developments in the science of biology, from the Renaissance to the genome revolution, in two parallel lines: one that explains how we gradually gained a mechanistic understanding of how life perpetuates itself through random alterations in DNA, with aging of its carriers as the inevitable by-product; and a much more complicated learning curve that thus far has merely provided the starting points of how we hope to gain a more complete understanding of how life forms are ordered at the molecular level and how this order turns into disorder during aging.

Keywords:   aging, biology, genetics, genomics

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