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SARSA case study in emerging infections$
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Angela McLean, Robert May, John Pattison, and Robin Weiss

Print publication date: 2005

Print ISBN-13: 9780198568193

Published to Oxford Scholarship Online: September 2007

DOI: 10.1093/acprof:oso/9780198568193.001.0001

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Influenza as a model system for studying the cross-species transfer and evolution of the SARS coronavirus

Influenza as a model system for studying the cross-species transfer and evolution of the SARS coronavirus

Chapter:
(p.24) CHAPTER 4 Influenza as a model system for studying the cross-species transfer and evolution of the SARS coronavirus
Source:
SARS
Author(s):

Robin M. Bush

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198568193.003.0004

The influenza virus is perhaps the most intensely studied of human pathogens. Effective vaccines have been available for over fifty years, yet influenza continues to present a major threat to public health. Does this bode ill for the control of SARS should it return? This chapter relates several recent evolutionary studies that provide insight into the ability of influenza to infect humans repeatedly throughout their lives. It reviews some common misconceptions about influenza which, in retrospect, were not far-fetched but simply based on limited data. These lessons may be pertinent if we hope to come quickly to grips with emerging infections such as SARS or avian flu.

Keywords:   influenza, pathogens, vaccination, public health, avian flu

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