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NeuroethicsDefining the issues in theory, practice, and policy$
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Judy Illes

Print publication date: 2004

Print ISBN-13: 9780198567219

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780198567219.001.0001

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Protecting human subjects in brain research: a pragmatic perspective

Protecting human subjects in brain research: a pragmatic perspective

Chapter:
(p.123) Chapter 9 Protecting human subjects in brain research: a pragmatic perspective
Source:
Neuroethics
Author(s):

Franklin G. Miller (Contributor Webpage)

Joseph J. Fins

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198567219.003.0009

This chapter elucidates ethical considerations in designing and carrying out clinical research on people with brain disorders based on an approach to research ethics derived from American philosophical pragmatism. Focusing on placebo-controlled trials of pharmacological treatments and deep-brain stimulation for psychiatric and neurological disorders, the chapter reflects how moral principles and standards can conflict when applied to contextually complex situations. To guide ethical judgment, it calls for a careful balancing of morally relevant considerations and an understanding of moral norms rather than categorical or absolute rules.

Keywords:   clinical research, neuroscience, research ethics, placebo-controlled trials, active-controlled trials

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