The life course plot in life course analysis
This chapter considers the life course in the context of an outcome in later life as related to early growth status, where each subject is assumed to have been measured as a child at two or more pre-specified ages. The analysis is by multiple regression, with the outcome as the dependent variable and the measurements at each age (expressed as z-scores) as the independent variables. This analysis highlights measurements at any particular age(s) that are predictive of outcome (size effects), and simultaneously flags the predictive value of changes in the measurement over different time intervals (i.e., growth effects). Size and growth are intimately related, and the life course plot helps to interpret the results.
Keywords: multiple regression, life course plots, interactions, functional data analysis, size and growth
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