Management of Patients with Brain Metastasis
Brain metastases indicate a dire turn in the course of disease. Cancer patients exhibiting brain metastases have fewer treatment options, poorer quality of life, and shortened lifespan. Diagnosis of brain metastases also affects the treatment management towards palliative care. This chapter focuses on the management of brain metastases in cancer patients. Brain metastases are the most common intra-cranial tumours, outnumbering primary brain tumours almost tenfold. They usually occurs in the advanced stages of cancer with widespread systemic metastasis and in patients who have failed multiple therapies. The management of brain metastases involves two components: the oncological (treatment of the malignant metastases) and neurological (management of the clinical manifestations of nervous-system involvement. In the following sections of the chapter, issues affecting clinical decision making are discussed. Such issues include diagnostic issues and safety issues.
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