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Coronary Heart Disease EpidemiologyFrom aetiology to public health$
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Michael Marmot and Paul Elliott

Print publication date: 2005

Print ISBN-13: 9780198525738

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780198525738.001.0001

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Prevention of coronary heart disease: findings from the Nurses’ Health Study and Health Professionals’ Follow-up Study

Prevention of coronary heart disease: findings from the Nurses’ Health Study and Health Professionals’ Follow-up Study

Chapter:
(p.654) Chapter 38 Prevention of coronary heart disease: findings from the Nurses’ Health Study and Health Professionals’ Follow-up Study
Source:
Coronary Heart Disease Epidemiology
Author(s):

F. B. Hu

W. C. Willett

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198525738.003.0039

This chapter discusses the contributions of the Nurses' Health Study (NHS) and Health Professionals' Follow-up Study (HPFS) to the nutritional epidemiology of coronary heart disease (CHD). Compelling evidence from these studies indicates that CHD is heavily influenced by dietary and lifestyle factors. Replacing saturated and trans fats with unsaturated fats, including sources of n-3 fatty acids, substituting whole grain forms of carbohydrate for refined grains and potatoes, consuming an abundance of fruits and vegetables, and controlling body weight will dramatically reduce the risk of CHD. The magnitude of benefit achievable through diet and lifestyle is large and substantially greater than that due to drug treatment of blood cholesterol or hypertension.

Keywords:   coronary heart disease, CHD, nutritional epidemiology, nutrition, dietary fats, carbohydrates, whole grains, fibre, antioxidants, smoking

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