Deficient glycoprotein glycosylation in humans and mice
This chapter discusses recent knowledge on gene knockout mice with deficient glycosyltransferases. It covers a large number of gene inactivation of glycosyltransferases, and should be valuable for anyone who want to look at the effect of one particular knockout. The pathological consequences of human patients with glycosylation defect are also described.
Keywords: gene knockout mice, glycosylation defects, glycosyltransferases, knockout
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