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Origins of the Human Brain$
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Jean-Pierre Changeux and Jean Chavaillon

Print publication date: 1996

Print ISBN-13: 9780198523901

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198523901.001.0001

The human genome

Chapter:
(p. 119 ) 7 The human genome
Source:
Origins of the Human Brain
Author(s):

Jean-Louis Mandel

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198523901.003.0007

This chapter attempts to identify the genes involved in brain development by giving a systemic analysis of the genomes of man, mice, and other model organisms. It also provides a detailed study of the function of such genes at the biochemical, cellular, or organismic level. An overview of the human genome is first illustrated followed by an analysis of the variability and evolution of the human genome. Also, a section on this chapter focuses on the genome project. The goal of this project is to obtain a complete sequence of the human genome and interpret it in terms of gene function. The mapping of disease genes is demonstrated as well to determine how this affects the development of specific brain structures.

Keywords:   brain development, human genome, evolution, the genome project, disease genes, brain structures

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