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Brain Damage, Brain Repair$
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James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

Print publication date: 2002

Print ISBN-13: 9780198523376

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198523376.001.0001

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Peripheral nerve regeneration

Peripheral nerve regeneration

Chapter:
(p.145) 11 Peripheral nerve regeneration
Source:
Brain Damage, Brain Repair
Author(s):

James W. Fawcett

Anne E. Rosser

Stephen B. Dunnett

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198523376.003.0011

Mammals have retained the ability to regenerate axons in the peripheral nervous system (PNS) and, if properly treated, can regain much of the function that is lost after peripheral nerve damage. Not only do the axons regenerate in the periphery, but they restore functional motor connections with muscles, and functional sensory connections with the skin. Nevertheless, peripheral nerve repair is seldom perfect, due both to problems of axon guidance and to other factors that can limit regeneration. There are, therefore, several problems that need to be solved before a regenerated peripheral nerve can completely restore normal function.

Keywords:   nerve regeneration, axons, peripheral nervous system, peripheral nerve damage, functional motor connections, functional sensory connections

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