Immune and Inflammatory Responses in the Nervous System
Nancy Rothwell and Sarah Loddick
Abstract
This new edition covers advances in understanding immunological and inflammatory responses in the nervous system, research driven by the potential to use knowledge of the molecules and mechanisms involved to intervene in, and arrest, neurodegenerative disease processes. This book covers developmental aspects of immune/inflammatory responses in the central nervous system (CNS), basic aspects of glial function, as well as inflammatory mediators, their mechanisms of action, clinical importance, and sites of infection. There is also coverage of the major diseases of the CNS, including stroke, brai ... More
This new edition covers advances in understanding immunological and inflammatory responses in the nervous system, research driven by the potential to use knowledge of the molecules and mechanisms involved to intervene in, and arrest, neurodegenerative disease processes. This book covers developmental aspects of immune/inflammatory responses in the central nervous system (CNS), basic aspects of glial function, as well as inflammatory mediators, their mechanisms of action, clinical importance, and sites of infection. There is also coverage of the major diseases of the CNS, including stroke, brain injury, multiple sclerosis, and Alzheimer's disease. Throughout, the focus is on the underlying basic neuroscience, clinical relevance, and the potential for therapeutic interventions. The book will be useful for improving the diagnosis of neuroimmune diseases and determining therapeutic measures.
Keywords:
immunological responses,
inflammatory responses,
nervous system,
neurodegenerative disease,
glial function,
inflammatory mediators,
action mechanisms,
clinical importance,
infection sites,
stroke
Bibliographic Information
| Print publication date: 2002 |
Print ISBN-13: 9780198509806 |
| Published to Oxford Scholarship Online: March 2012 |
DOI:10.1093/acprof:oso/9780198509806.001.0001 |
Authors
Affiliations are at time of print publication.
Nancy Rothwell, Editor
School of Biological Sciences, University of Manchester, UK
Sarah Loddick, Editor
School of Biological Sciences, University of Manchester UK
More
Less