The parahippocampal region in temporal lobe epilepsy
Anatomical studies had clearly shown that the hippocampus was not an isolated area, but quite closely tied to other limbic structures, including regions that subsequently have been shown to have substantial involvement in temporal lobe epilepsy (TLE) and animal models of epilepsy. These structures, such as the perirhinal cortex and entorhinal cortex, have in common their location within the parahippocampal region. These studies formed the basis of theories that extrahippocampal structures, especially those in the parahippocampal region, play an important role in seizures of temporal origin.
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