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Lysosomal Disorders of the BrainRecent Advances in Molecular and Cellular Pathogenesis and Treatment$
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Frances Platt and Steven Walkley

Print publication date: 2004

Print ISBN-13: 9780198508786

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780198508786.001.0001

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Cell-mediated delivery systems

Cell-mediated delivery systems

Chapter:
(p.339) Chapter 14 Cell-mediated delivery systems
Source:
Lysosomal Disorders of the Brain
Author(s):

Kostantin Dobrenis

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780198508786.003.00014

Diseases that involve the central nervous system (CNS) pose one of the most difficult challenges in human therapy. Cell-mediated therapy (CMT) is a uniquely complex and powerful approach that offers an unparalleled advantage. This chapter reviews work in the area of CMT with a bias towards understanding the critical mechanisms that underlie successful CMT for CNS storage disease. It highlights the advantages offered by employing cells as the therapeutic agent.

Keywords:   central nervous system, cell-mediated therapy, lysosomal storage disorders, CMT

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