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Quantitative Methods in Neuroscience
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Quantitative Methods in Neuroscience: A Neuroanatomical Approach

Stephen M. Evans, Ann Marie Janson, and Jens Randel Nyengaard

Abstract

Stereology is a valuable tool for neuroscientists, allowing them to obtain three-dimensional information from two-dimensional measurements made on appropriately sampled sections (usually obtained from histological sections or MRI/CT/PET scans). This 3-D information is invaluable in correlating structural/functional relationships in the pursuit of far greater understanding of the function of the central nervous system. However, in carrying out such measurements, often based on limited data sets, there is a risk of experimenter bias. An important feature of modern design based stereology is to b ... More

Keywords: stereology, disector, fractionator, sampling, length, surface area, volume, number, neuroscience

Bibliographic Information

Print publication date: 2004 Print ISBN-13: 9780198505280
Published to Oxford Scholarship Online: September 2009 DOI:10.1093/acprof:oso/9780198505280.001.0001

Authors

Affiliations are at time of print publication.

Stephen M. Evans, editor
Pharmaimaging Limited, Grangemouth, Scotland

Ann Marie Janson, editor
Department of Neuroscience, Karolinska Institute, Stockholm, Sweden

Jens Randel Nyengaard, editor
Stereological Research Laboratory, Aarhus University Hospital, Aarhus, Denmark

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