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Integrative Neuroscience and Personalized Medicine$
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Evian Gordon, MD, PhD and Stephen Koslow, PhD

Print publication date: 2010

Print ISBN-13: 9780195393804

Published to Oxford Scholarship Online: January 2011

DOI: 10.1093/acprof:oso/9780195393804.001.0001

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Stress and the Impact of Personalized Medicine

Stress and the Impact of Personalized Medicine

(p.73) 5 Stress and the Impact of Personalized Medicine
Integrative Neuroscience and Personalized Medicine

Charles F. Gillespie

Elisabeth B. Binder

Paul E. Holtzheimer

Charles B. Nemeroff

Oxford University Press

This report summarizes a number of the epigenetic influence on the development and treatment of anxiety and mood disorders. The focus taken here is on the impact of stress and stressors on the endocrine axis and their effects on the anxiety and mood disorders. There have been a number of interesting leads as to what the relevant important genetic components may be however none have been studied sufficiently to be used as Personalized Medicine markers for anxiety or depression.

Keywords:   Anxiety, Depression, Stress, Stressors, Abuse, Neuroendocrine, ghypothalamic-pituitary-adrenal axis, SNPs, Genes, Brain Imaging

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