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Dopamine Handbook$
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Leslie Iversen, Susan Iversen, Stephen Dunnett, and Anders Bjorklund

Print publication date: 2009

Print ISBN-13: 9780195373035

Published to Oxford Scholarship Online: February 2010

DOI: 10.1093/acprof:oso/9780195373035.001.0001

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Dopaminergic Mechanisms in Drug-Seeking Habits and the Vulnerability to Drug Addiction

Dopaminergic Mechanisms in Drug-Seeking Habits and the Vulnerability to Drug Addiction

Chapter:
(p.389) 8.2 Dopaminergic Mechanisms in Drug-Seeking Habits and the Vulnerability to Drug Addiction
Source:
Dopamine Handbook
Author(s):

Barry J. Everitt

David Belin

Jeffrey W. Dalley

Trevor W. Robbins

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195373035.003.0027

This chapter begins with a discussion of the notion that dopamine (DA) transmission provides a neurochemical mechanism of reinforcement in the brain. It then covers the molecular mechanisms of action of addictive drugs, Pavlovian conditioning, addictive drugs and cellular models of learning and plasticity, and dopaminergic mechanisms in the vulnerability to drug addiction.

Keywords:   dopamine, reinforcement, drug abuse, addiction

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