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Dopamine Handbook$
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Leslie Iversen, Susan Iversen, Stephen Dunnett, and Anders Bjorklund

Print publication date: 2009

Print ISBN-13: 9780195373035

Published to Oxford Scholarship Online: February 2010

DOI: 10.1093/acprof:oso/9780195373035.001.0001

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Dopamine’s Influence on Prefrontal Cortical Cognition: Actions and Circuits in Behaving Primates

Dopamine’s Influence on Prefrontal Cortical Cognition: Actions and Circuits in Behaving Primates

Chapter:
(p.230) 5.3 Dopamine’s Influence on Prefrontal Cortical Cognition: Actions and Circuits in Behaving Primates
Source:
Dopamine Handbook
Author(s):

Amy F.T. Arnsten

Susheel Vijayraghavan

Min Wang

Nao J. Gamo

Constantinos D. Paspalas

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195373035.003.0016

This chapter summarizes current knowledge of dopamine (DA) and DA receptor localization in primate prefrontal cortex (PFC), and the powerful influences of DA on PFC physiology and cognitive function. It begins with an overview of PFC function, physiology, and circuitry. It then discusses the anatomy of DA and its receptors in the primate PFC, the effects of DA on PFC physiology and function, and the role of changes in DA transmission in PFC in several neuropsychiatric disorders.

Keywords:   dopamine, prefrontal cortex, primates, cognitive function, neuropsychiatric disorders

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