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Tempests, Poxes, Predators, and PeopleStress in Wild Animals and How They Cope$
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John C. Wingfield and L.Michael Romero

Print publication date: 2015

Print ISBN-13: 9780195366693

Published to Oxford Scholarship Online: December 2015

DOI: 10.1093/acprof:oso/9780195366693.001.0001

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Mediators of Stress

Mediators of Stress

Chapter:
(p.23) 2 Mediators of Stress
Source:
Tempests, Poxes, Predators, and People
Author(s):

L. Michael Romero

John C. Wingfield

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195366693.003.0002

This chapter provides an introduction to the major components of the neuroendocrine/endocrine systems that have major roles as mediators of stress—or rather, the responses to stress. This overview includes the classic hypothalamo-pituitary-endocrine gland axes that regulate many aspects of morphology, physiology and behavior. A comparative approach is taken because the anatomy of these axes varies across vertebrate taxa. The focus is primarily on the hypothalamo-pituitary-adrenal cortex axis and the glucocorticoids that are secreted as a result; and on the catecholamines from the adrenal medulla, epinephrine, and norepinephrine. Included are discussions of receptor binding, and circadian and negative feedback regulation

Keywords:   hypothalamus, pituitary, adrenal, catecholamines, epinephrine, glucocorticoids, negative feedback, circadian, receptors

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