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Adolescent Psychopathology and the Developing BrainIntegrating Brain and Prevention Science$
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Daniel Romer and Elaine F. Walker

Print publication date: 2007

Print ISBN-13: 9780195306255

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195306255.001.0001

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Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction

Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction

Chapter:
(p.388) Chapter 17 Brain Development as a Vulnerability Factor in the Etiology of Substance Abuse and Addiction
Source:
Adolescent Psychopathology and the Developing Brain
Author(s):

Charles P. O’Brien

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195306255.003.0017

This chapter reviews the deleterious effects of addictive drugs on brain development and what is known about ways to reverse these effects. It shows that adolescence is a vulnerable period for initiating substance abuse. Progression from use to abuse to addiction is influenced by multiple, simultaneous variables categorized in the medical model as agent, host, and environment. However, the majority of adolescents who experiment with drugs do not progress to addiction, although they could experience harm or fatalities from acute effects and accidents. Those beginning at a younger age have the highest risk of developing an addiction and the poorest results when they later seek treatment as adults.

Keywords:   addiction risk, adolescent vulnerability, adolescent brain development, substance use

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