Accessing Files of Sequences from Databases
This chapter gives instructions for getting to the vast databases of NCBI and coming away with the files of sequence wanted. Sequence databases are the new museums of the genomic age. The grandest of them all is at the National Center for Biotechnology Information (NCBI) and is publicly available. The databases at NCBI are among the best maintained, fastest, and most frequently updated of any public databases in existence. Instructions are given for creating and naming files of sequence data and storing the files where the Perl program can find them. Because so much data is stored in so many files, understanding how to open files and read sequence and other data from files is one of the important steps toward programming ‘in the large’. Side boxes include: ‘Ten Ways to look at DNA’.
Keywords: sequence files, files, input, output, end of file, file modes
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