A Multimodal Analysis of Structure and Function in Broca’s Region
The term “Broca region” is used inconsistently in the literature with respect to the underlying microstructure. It is often applied as a clinical and/or historical concept of a center of language processing without keeping in mind a certain microstructurally defined cortical area. However, it appears yet undecided whether the concept of “Broca region” is more than a historical one or an imprecise descriptor of a language center, that is, whether a functionally and/or anatomically defined unit is beyond the term. Thus, it seems to be reasonable, at least, to investigate this question using a combination of anatomical approaches (multimodal analysis of microstructure) with functional analysis of language (psycholinguistics) and, finally, clinical studies. This chapter focuses on the microstructure of the putative Broca region and how this anatomical information can be used for the interpretation of data from functional imaging studies (fMRI, positonemission tomography (PET)) of language-related tasks.
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