Disorders of the Self in Dementia
The self is experienced as a unified whole, yet self-representation by the brain requires an interconnected hierarchy of parts that can be selectively dismantled by neurological disease. This idea is readily illustrated with the dementias, in which progressive regional degeneration can alter one aspect of the self while sparing others. This chapter summarizes the evolution of self-representational capacities, outlines the acquisition of the self during human development, and offers associations between the self's functional subcomponents and the brain structures that support them. From that perspective it discusses how the self can be unmade in patients with dementia.
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