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Biology of Aggression$
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Randy J. Nelson

Print publication date: 2005

Print ISBN-13: 9780195168761

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195168761.001.0001

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The Role of Estrogen Receptors in the Regulation of Aggressive Behaviors

The Role of Estrogen Receptors in the Regulation of Aggressive Behaviors

Chapter:
(p.231) 10 The Role of Estrogen Receptors in the Regulation of Aggressive Behaviors
Source:
Biology of Aggression
Author(s):

Sonoko Ogawa

Masayoshi Nomura

Elena Choleris

Donald Pfaff

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195168761.003.0010

At least two types of estrogen receptors (ERs), the classical ER-α and the more recently identified ER-β, have been localized in the central nervous system. ER-α and ER-β are very similar estrogen binding proteins that act as ligand-dependent transcription factors. Although somewhat overlapping, brain distributions of ER-α and ER-β are not identical. This chapter summarizes current knowledge of the possible differential roles played by the two types of ERs in the expression of aggressive behavior. It also discusses potential brain mechanisms of ER-mediated regulation of aggression.

Keywords:   aggression, mice, male aggressive behavior, female aggressive behavior

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