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Excitatory Amino Acid Transmission in Health and Disease
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Excitatory Amino Acid Transmission in Health and Disease

Robert Balazs, Richard J. Bridges, Carl W. Cotman, and Cheryl A. Cotman

Abstract

This book provides a comprehensive, easy-to-read survey of excitatory amino acids and synaptic transmission. It begins with descriptions of the structure, function, and pharmacology of both the ionotropic and the metabotropic glutamate receptors and the glutamate transporters. Subsequent chapters deal with molecular aspects of the regulation of glutamatergic transmission, including receptor trafficking, the role of glutamate transport, the unique molecular architecture of the synapses (post-synaptic density), and the signal transduction pathways mediated by glutamate. Also unique to the book i ... More

Keywords: amino acids, synaptic transmission, glutamate receptors, glutamate transporters, neurological diseases, synapses, synaptic plasticity, long-term potentiation, long-term depression

Bibliographic Information

Print publication date: 2005 Print ISBN-13: 9780195150025
Published to Oxford Scholarship Online: January 2010 DOI:10.1093/acprof:oso/9780195150025.001.0001

Authors

Affiliations are at time of print publication.

Robert Balazs, author
University of California at Irvine

Richard J. Bridges, author
University of Montana

Carl W. Cotman, author
University of California at Irvine

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