Irreversible Discrete Disease Processes: Silica and Lung Cancer
The introduction to discrete irreversible processes in Chapter 13 noted that there are two important examples of groups of diseases that follow this pattern: immune sensitization and carcinogenesis. Unfortunately, much less is known about the intermediate steps in sensitization, and few examples of biologically based models have been applied to studies of immune diseases in humans, as was noted. This chapter discusses carcinogenesis, which has been more extensively studied.
Keywords: lung cancer, carcinogenesis, silica
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