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Principles of Frontal Lobe Function$
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Donald T. Stuss and Robert T. Knight

Print publication date: 2002

Print ISBN-13: 9780195134971

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195134971.001.0001

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Normal Development of Prefrontal Cortex from Birth to Young Adulthood: Cognitive Functions, Anatomy, and Biochemistry

Normal Development of Prefrontal Cortex from Birth to Young Adulthood: Cognitive Functions, Anatomy, and Biochemistry

Chapter:
(p.466) 29 Normal Development of Prefrontal Cortex from Birth to Young Adulthood: Cognitive Functions, Anatomy, and Biochemistry
Source:
Principles of Frontal Lobe Function
Author(s):

Adele Diamond

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195134971.003.0029

The prefrontal cortex (PFC) undergoes one of the longest periods of development of any brain region, taking over two decades to reach full maturity in humans. This chapter focuses on normal development, dividing it into the following epochs: 0-1 years, 1-3 years, 3-7 years, and 7 years through early adulthood. For each epoch, it summarizes some of what is known about (a) the development of the working memory and inhibitory control functions that depend on PFC and (b) the anatomical and biochemical developmental changes in PFC during that period.

Keywords:   brain development, working memory, inhibitory control functions, prefrontal cortex

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