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Principles of Frontal Lobe Function$
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Donald T. Stuss and Robert T. Knight

Print publication date: 2002

Print ISBN-13: 9780195134971

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195134971.001.0001

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The Role of Prefrontal Cortex in Normal and Disordered Cognitive Control: A Cognitive Neuroscience Perspective

The Role of Prefrontal Cortex in Normal and Disordered Cognitive Control: A Cognitive Neuroscience Perspective

Chapter:
(p.428) 27 The Role of Prefrontal Cortex in Normal and Disordered Cognitive Control: A Cognitive Neuroscience Perspective
Source:
Principles of Frontal Lobe Function
Author(s):

Todd S. Braver

Jonathan D. Cohen

Deanna M. Barch

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195134971.003.0027

This chapter presents a theory of prefrontal cortex (PFC) function using the connectionist computational modeling framework. This modeling approach involves three components: (1) computational analysis of the critical processing mechanisms required for cognitive control; (2) use of neurobiologically plausible principles of information processing; and (3) implementation and simulation of cognitive tasks and behavioral performance. The chapter describes behavioral and neuroimaging data on healthy young adults that validate critical components of the model. It then summarizes the application of the model to the clinical domain. These studies highlight the power of the cognitive neuroscience approach by demonstrating how a single, integrated account of PFC function can capture a wide range of data from different methodologies and multiple populations.

Keywords:   prefrontal cortex function, computational modeling, cognitive control, PFC, computational analysis

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