The Biology of Meaning
The frontal and temporal lobes, along with the basal ganglia, are the most intensively studied regions of the brain in relation to schizophrenia. This chapter describes the behavioral and biological characteristics of the temporal lobes, with a focus on the left temporal area. It shows that some psychological functions associated with the left temporal lobe, notably memory but also language comprehension and selective attention, are probably deficient in about three-quarters of schizophrenia patients. Although there is no replicated evidence of complete separation of patient and healthy samples, the findings of disturbed semantic processing in many patients are substantial in magnitude. On the other hand, there is no evidence that defective temporal lobe cognition is a necessary part of schizophrenia. There are substantial numbers of patients with the illness who perform normally on these tests.
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