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Psychiatric EpidemiologySearching for the Causes of Mental Disorders$
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Ezra Susser, Sharon Schwartz, Alfredo Morabia, and Evelyn Bromet

Print publication date: 2006

Print ISBN-13: 9780195101812

Published to Oxford Scholarship Online: September 2009

DOI: 10.1093/acprof:oso/9780195101812.001.0001

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Genetic Association Studies

Genetic Association Studies

Chapter:
(p.341) 29 Genetic Association Studies
Source:
Psychiatric Epidemiology
Author(s):

Ezra Susser (Contributor Webpage)

Sharon Schwartz

Alfredo Morabia

Evelyn J. Bromet

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195101812.003.29

This chapter focuses on genetic association studies. The goal of genetic association studies is to investigate the effects of genotypic variation on disease risk. These designs are built on a concept of a genetic cause that closely resembles the concept of a risk factor in epidemiology. Moreover, they correspond well to designs previously articulated by risk factor epidemiologists. Thus, the concepts and methods of risk factor epidemiology are particularly useful in this context.

Keywords:   cohort study, genetic association study, case-control design, family-based design, case-parent triad design

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