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The Hippocampus Book$
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Per Andersen, Richard Morris, David Amaral, Tim Bliss, and John O'Keefe

Print publication date: 2006

Print ISBN-13: 9780195100273

Published to Oxford Scholarship Online: May 2009

DOI: 10.1093/acprof:oso/9780195100273.001.0001

Molecular Mechanisms of Synaptic Function in the Hippocampus: Neurotransmitter Exocytosis and Glutamatergic, GABAergic, and Cholinergic Transmission

Chapter:
(p.243) 7 Molecular Mechanisms of Synaptic Function in the Hippocampus: Neurotransmitter Exocytosis and Glutamatergic, GABAergic, and Cholinergic Transmission
Source:
The Hippocampus Book
Author(s):

Osten Pavel

Wisden William

Sprengel Rolf

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195100273.003.0007

This chapter discusses the molecular biology of hippocampal cells with particular emphasis on synaptic function. It starts by describing the basis of all signal transmission processes, the release of the signaling transmitter from the presynaptic terminal. It then details the key glutamate and GABA receptors responsible for the “nuts and bolts” of hippocampal chemical transmission. As an example of modulatory transmission, it discusses how acetylcholine muscarinic and nicotinic receptors influence information flow in the hippocampal cell types.

Keywords:   excitatory transmission, inhibitory transmission, signal transmission, glutamate, GABA receptors

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