A life course approach to musculoskeletal ageing: muscle strength, osteoporosis, and osteoarthritis
This chapter reviews the development and aging of three key components of the musculoskeletal system (muscle, bone, and cartilage), and considers their consequences for adult disease. Musculoskeletal disorders are an important cause of morbidity and functional impairment in the general population. They are strongly age-related, and tend to occur more frequently among women than men. For the three important causes of musculoskeletal disability(age-related declines in muscle strength; osteoporosis; and osteoarthritis) evidence now exists to suggest aetiological factors acting throughout the life course.
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