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The NMDA Receptor$
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G. L. Collingridge and J. C. Watkins

Print publication date: 1995

Print ISBN-13: 9780192625021

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780192625021.001.0001

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NMDA receptors and developmental plasticity in visual neocortex

NMDA receptors and developmental plasticity in visual neocortex

Chapter:
(p.313) 14 NMDA receptors and developmental plasticity in visual neocortex
Source:
The NMDA Receptor
Author(s):

ALAIN ARTOLA

WOLF SINGER

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780192625021.003.0014

Learning can be considered as a stimulus- and, hence, activity-dependent neuronal process that leads to a lasting change of stimulus-response relationships. The formation of a memory trace may thus be considered as a modification of the neuronal program that specifies input-output functions. This program is contained in the architecture of neuronal connectivity and in the transfer functions of these connections. Thus, any activity-dependent process that modifies, in a sufficiently stable and long-lasting way, the interactions between pairs of neurones could serve as a mechanism of learning.

Keywords:   NMDA receptors, neuronal processes, learning, memory traces, neuronal connectivity

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