Jump to ContentJump to Main Navigation
The NMDA Receptor$
Users without a subscription are not able to see the full content.

G. L. Collingridge and J. C. Watkins

Print publication date: 1995

Print ISBN-13: 9780192625021

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780192625021.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2018. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a monograph in OSO for personal use (for details see www.oxfordscholarship.com/page/privacy-policy).date: 23 October 2018

The importance of NMDA receptors in the processing of spinal primary afferent input

The importance of NMDA receptors in the processing of spinal primary afferent input

Chapter:
(p.266) 11 The importance of NMDA receptors in the processing of spinal primary afferent input
Source:
The NMDA Receptor
Author(s):

R. H. EVANS

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780192625021.003.0011

This chapter covers the following aspects which are relevant to the role of N-methyl-d-aspartate (NMDA) receptors in spinal neurotransmission: the involvement of NMDA receptors and the co-agonist glycine site in long duration spinal reflexes elicited from dorsal roots; the relationship between glutamatergic and peptidergic transmission from primary afferent C fibres; and the selective depression of NMDA-receptive excitatory pathways by analgesic and myorelaxant drugs. It has been reported that long duration synaptic potentials in spinal preparations are a property of early development because in rats older than ten days, synaptic potentials are of much shorter duration than in younger rats. However, such comparisons between spinal root recordings from animals of different ages should be cautiously interpreted.

Keywords:   NMDA receptors, spinal neurotransmission, glycine, spinal reflexes, primary afferent C fibres, synaptic potentials

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .