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The Pharmacology of Vascular Smooth Muscle
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The Pharmacology of Vascular Smooth Muscle

C. J. Garland and J. A. Angus

Abstract

This book provides an understanding of how events at the cellular level impact on the cardiovascular system as a whole. Advances in knowledge are highlighted and all the themes are presented from the single cell (smooth muscle endothelial and nerve) level through to the blood vessel wall to the vascular system as a functional system. This book provides an introduction to wide-ranging pharmacological principles and major techniques in this subject area, and is a source of background literature for research in vascular pharmacology.

Keywords: blood vessel wall, smooth muscle cell, cellular level, cardiovascular system, nerve cell, pharmacological techniques, vascular pharmacology

Bibliographic Information

Print publication date: 1996 Print ISBN-13: 9780192623874
Published to Oxford Scholarship Online: March 2012 DOI:10.1093/acprof:oso/9780192623874.001.0001

Authors

Affiliations are at time of print publication.

C. J. Garland, editor
University of Bristol

J. A. Angus, editor
University of Melbourne

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Contents

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2. Isolated tissue techniques

Michael J. Lew, and Grant A. McPherson

3. Single cell techniques

Alison M. Gurney

4. In vivo techniques and analysis

J. A. Angus, C. E. Wright, K. Sudhir, and G. J. Jennings

5. Initiation of smooth muscle response

A. M. Shaw, and J. C. McGrath

7. Cell signalling pathways involved in the regulation of vascular smooth muscle contraction and relaxation

Kevin Malarkey, Dorothy Aidulis, Christopher M. Belham, Anne Graham, Angela McLees, Andrew Paul, and Robin Plevin

8. Neuroeffector transmission in arteries, arterioles, and veins

Susan E. Luff, G. D. S. Hirst, and T. C. Cunnane

9. Cotransmission

G. Burnstock, and V. Ralevic

11. Pharmacology of the cerebral circulation

P. A. T. Kelly, and C. J. Garland

13. Pharmacology of the renal circulation

David P. Brooks, and Richard M. Edwards

14. Atherosclerosis

Xiao-Jun Du, and Anthony M. Dart

16. The cerebral microvascular endothelium in ischaemia

A. Lorris Betz, and Fausto Iannotti

17. Regulation of vascular smooth muscle tone in sepsis

Richard G. Bogle, and Patrick Vallance

18. Hypertension

Jaye P. F. Chin, and Anthony M. Dart

19. Pulmonary hypertension

George Cremona, and Tim Higenbottam

End Matter