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Migraine: A Spectrum of Ideas
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Migraine: A Spectrum of Ideas

Merton Sandler and Geralyn M. Collins

Abstract

Thirty per cent of all women and ten per cent of all men experience migraine. This crippling illness does not kill, but its high morbidity poses a massive economic problem and gives rise to considerable suffering. Its main manifestation, headache, is subjective, and there are no animal models. This makes traditional research approaches difficult, and has led to a variety of research strategies. Chapters here present the numerous advances that have been made over the past two decades in our understanding of this disorder, and discuss in depth the position of migraine research today and the dire ... More

Keywords: migraine, crippling illness, high morbidity, economic problem, headache, animal models, traditional research approaches, research strategies, migraine research, disorder

Bibliographic Information

Print publication date: 1990 Print ISBN-13: 9780192618108
Published to Oxford Scholarship Online: March 2012 DOI:10.1093/acprof:oso/9780192618108.001.0001

Authors

Affiliations are at time of print publication.

Merton Sandler, editor
University of London

Geralyn M. Collins, editor

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Contents

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Front Matter

1. Introduction

Merton Sandler

4. Genetic epidemiology of migraine

Kathleen R. Merikangas

7. Vasomotor functions of trigeminovascular fibres: inferences from lesion studies

Michael A. Moskowitz, Damianos E. Sakas, Michihisa Kano, Hermes A. Kontos, and Enoch P. Wei

8. Regional cerebral blood flow in migraine

Jes Olesen, Tom Skyhøj Olsen, and Lars Friberg

16. General discussion I

Merton Sandler, and Geralyn M. Collins

18. Novel agents affecting enkephalinergic and histaminergic transmissions in brain

J.C. Schwartz, B. Giros, C. Gros, C. Llorens-Cortes, J.M. Arrang, M. Garbarg, and H. Pollard

19. The biochemical basis of migraine predisposition

Vivette Glover, and Merton Sandler

20. Depression and migraine

Kathleen R. Merikangas, and Jules Angst

26. General discussion II

Merton Sandler, and Geralyn M. Collins

End Matter