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Cost-Effectiveness in Health and Medicine$
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Peter J. Neumann, Theodore G. Ganiats, Louise B. Russell, Gillian D. Sanders, and Joanna E. Siegel

Print publication date: 2016

Print ISBN-13: 9780190492939

Published to Oxford Scholarship Online: November 2016

DOI: 10.1093/acprof:oso/9780190492939.001.0001

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Designing a Cost-Effectiveness Analysis

Designing a Cost-Effectiveness Analysis

Chapter:
(p.75) 4 Designing a Cost-Effectiveness Analysis
Source:
Cost-Effectiveness in Health and Medicine
Author(s):

Douglas K. Owens

Joanna E. Siegel

Mark J. Sculpher

Joshua A. Salomon

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780190492939.003.0004

This chapter provides an overview of how to design a cost-effectiveness analysis (CEA). The chapter highlights the importance of early conceptualization and planning steps to define the objectives, the research question, the perspective(s), the intervention(s), the target population, the comparators, the scope, the time horizon, and the analysis plan for a cost-effectiveness study. The chapter recommends that analysts conduct Reference Case analyses from both the healthcare sector perspective and the societal perspective. We also recommend that analysts use an Impact Inventory, which lists the consequences across sectors (e.g., healthcare, education, criminal justice system) affected by an intervention, and that they develop a written protocol that details key aspects of the CEA’s design and conduct.

Keywords:   Cost-effectiveness analysis, design, objectives, intervention, target population, comparators, time horizon, analysis plan, Reference Case, written protocol

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