A brief history of the anhedonia hypothesis
This chapter discusses the history of the so-called anhedonia hypothesis. The term anhedonia was first used in 1978 in connection with the assertion that pimozide blocks the reward quality of food. The anhedonia hypothesis was based largely on studies of psychomotor stimulant, brain stimulation, and food and water reinforcement. It also discusses brain stimulation reward, opiate reinforcement, and several other drugs of abuse that activate the dopamine system.
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