Plasticity in Adult M1 Cortex During Motor Skill Learning
This chapter reviews the results of a large body of studies that examined the cerebral plasticity in the primary motor cortex (M1) using neurophysiological approaches in monkeys and rodents, or behavioral experiments using modern brain mapping techniques such as positron emission tomography (PET), functional magnetic resonance imaging (fMRI), and transcranial magnetic stimulation (TMS) in human adults. It describes the plastic changes that occur within M1 over the course of learning in order to determine their role in the acquisition, consolidation, and long-term retention of new motor skilled behaviors. It discusses the physiological and neurobiological correlates of such plasticity to give insights into the underlying mechanisms for the representational functional changes associated with the learning and retention of a motor skill.
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