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Mechanisms of Synaptic Transmission$
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Joseph D. Robinson

Print publication date: 2001

Print ISBN-13: 9780195137613

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780195137613.001.0001

Receptor Structures and Receptor Families(1983–1990)

Chapter:
(p. 199 ) 8 Receptor Structures and Receptor Families(1983–1990)
Source:
Mechanisms of Synaptic Transmission
Author(s):

Joseph D. Robinson

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780195137613.003.0008

This chapter discusses two major classes of receptor function and structure: oligomeric subunits surrounding an ion-conducting pore formed a ligand-gated ion channel that opened when neurotransmitters filled the binding sites and monomeric proteins with seven transmembrane segments formed receptors that activated a coupled G-protein. With the first class, chemical signals or neurotransmitters were converted into electrical signals. With the second, chemical signals were converted to different chemical signals: G-proteins that then interacted with various enzymes and channels to elicit both chemical and electrical responses.

Keywords:   receptor, oligomeric subunits, monomeric protein, chemical signals, neurotransmitters, electrical signals

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