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AlcoholScience, Policy and Public Health$
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Peter Boyle, Paolo Boffetta, Albert B. Lowenfels, Harry Burns, Otis Brawley, Witold Zatonski, and Jürgen Rehm

Print publication date: 2013

Print ISBN-13: 9780199655786

Published to Oxford Scholarship Online: May 2013

DOI: 10.1093/acprof:oso/9780199655786.001.0001

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Liver and pancreatic tumours

Liver and pancreatic tumours

Chapter:
(p.229) Chapter 27 Liver and pancreatic tumours
Source:
Alcohol
Author(s):

Patrick Maisonneuve

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199655786.003.0027

This chapter discusses the link between alcohol consumption and liver and pancreatic cancer. Alcohol is known to promote inflammation of both the liver and the pancreas, leading to liver cirrhosis and pancreatitis. These two chronic conditions have been in turn associated with increased risk of liver and pancreatic cancer. While liver cirrhosis precedes the development of liver cancer in most of cases, long-standing chronic pancreatitis precedes pancreatic cancer in a very small proportion of cases. Therefore, the contribution of heavy alcohol intake on the risk of developing cancer, mediated by chronic inflammation, varies widely for both organs.

Keywords:   alcohol consumption, alcohol intake, liver cancer, pancreatic cancer, cancer risk, liver cirrhosis, pancreatitis

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