Abstract: This chapter consolidates the constraints on metaphysics as a unification of science by requiring that a metaphysical hypothesis respect the constraint of the principle of naturalistic closure (PNC). Floridi criticizes what he calls the “eliminativist” interpretation of OSR, the view that self-subsistent individuals do not exist, on the grounds that it lets the tail of the quantum-theoretic problems over entanglement wag the dog of our general world-view. However, the Primacy of Physics Constraint (PPC), according to which failure of an interpretation of special-science generalizations to respect negative implications of physical theory is grounds for rejecting such generalizations, is endorsed in this chapter. Thus, Floridi's modus tollens may be considered a modus ponens: if the best current interpretation of fundamental physics says there are no self-subsistent individuals, then special sciences had better admit, for the sake of unification, of an ontological interpretation that is compatible with a non-atomistic metaphysics. The PNC is invoked again independently.

Keywords: rainforest realism, Floridi, principle of naturalistic closure, primacy of physics constraint, special sciences, real patterns, non-atomistic metaphysics,