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Macromolecular Crystallography
conventional and high-throughput methods
Sanderson, Mark R.
Randall Division of Cell and Molecular Biophysics, King's College London, UK.
Skelly, Jane V.
Medway School of Science, University of Greenwich, UK.
Print publication date: 2007 (this edition)
Published to Oxford Scholarship Online: September 2007
Print ISBN-13: 978-0-19-852097-9
CHAPTER 16 Virus crystallography
doi:10.1093/acprof:oso/9780198520979.003.0016
Elizabeth E. Fry
Nicola G. A. Abrescia
David I. Stuart
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Contents
Full Book Contents
Preface
CHAPTER 1 Classical cloning, expression, and purification
CHAPTER 2 High-throughput cloning, expression, and purification
CHAPTER 3 Automation of non-conventional crystallization techniques for screening and optimization
CHAPTER 4 First analysis of macromolecular crystals
CHAPTER 5 In-house macromolecular data collection
CHAPTER 6 Solving the phase problem using isomorphous replacement
CHAPTER 7 Molecular replacement techniques for high-throughput structure determination
CHAPTER 8 MAD phasing
CHAPTER 9 Application of direct methods to macromolecular structure solution
CHAPTER 10 Phase refinement through density modification
CHAPTER 11 Getting a macromolecular model: model building, refinement, and validation
CHAPTER 12 High-throughput crystallographic data collection at synchrotrons
CHAPTER 13 Electron density fitting and structure validation
CHAPTER 14 RNA crystallogenesis
CHAPTER 15 Crystallography in the study of protein–DNA interaction
CHAPTER 16 Virus crystallography
CHAPTER 17 Macromolecular crystallography in drug design
Index
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