Neuroendocrine and Autonomic

The primary goal of this book is to summarize and synthesize recent advances in the biological study of aggression. Other than maternal aggression, most aggressive encounters among human and non-human animals represent a male proclivity; thus, most of the research in this book describes and discusses studies using the most appropriate murine model: testosterone-dependent offensive inter-male aggression, which is typically measured in resident-intruder or isolation-induced aggression tests. The research emphasizes various molecules that have been linked to aggression tests. It also emphasizes various molecules that have been linked to aggression by the latest gene-targeting and pharmacological techniques. Although the evidence continues to point to androgens and serotonin (5-HT) as major hormonal and neurotransmitter factors in aggressive behavior, recent work with GABA, dopamine, vasopressin, and other factors, such as nitric oxide, has revealed significant interactions with the neural circuitry underlying aggression.

This book presents a simple description of the biological mechanisms that are involved in the determination of sexual orientation in animals and also presumably in humans. Using scientific studies published over the last few decades, it argues that sexual orientation, both homosexual and heterosexual, is under the control of embryonic endocrine and genetic phenomena in which there is little room for individual choice. The book begins with animal studies of the hormonal and neural mechanisms that control the so-called instinctive behaviors and analyzes how this animal work may potentially apply to humans. The book does not focus exclusively on homosexuality, however. Instead, the book acts as a broader guide to the biological basis of sexual orientation, and also discusses important gender differences that may influence sexual orientation.

Aromatase—or estrogen, as it is commonly known—is present in the brain and has been the subject of much recent research, not only with regard to menopause and the dwindling supply of estrogen and its impact on cognition, but the role estrogen in aging and plasticity in the brain. This book provides a review of what is known about aromatase and its distribution and regulation in the brain, and its many effects on behavior. The volume covers research on mammals (from rats to monkeys), as well as work done on birds, reptiles and amphibians, and fishes. Topics range from behavioral effects (genomic) of locally produced estrogen in the brain; aromatase and sexual differentiation; rapid changes in brain aromatase as a result of environmental effects; aromatase and brain repair; the rapid effects of estrogens on behavior; rapid effect of estrogen on sensory (auditory) processing; and a concluding statement on current challenges to research.

How important are biological factors, such as hormones, in shaping our sexual destinies? This book brings social developmental, biological, and clinical psychological perspectives to bear on the factors that shape our development as male or female and that cause individuals within each sex to differ from one another in sex-related behaviors. Topics covered include sexual orientation, childhood play; spatial, mathematical, and verbal abilities; nurturance, aggression, dominance, handedness, brain structure, and gender identity.

Central autonomic circuits in the brain and spinal cord are essential to vertebrate life. They control all basic bodily functions, including blood pressure, body temperature regulation, digestion, and reproduction. This book presents the extraordinary advances that have been made over the last twenty years in the understanding of how our central nervous system controls autonomic function. The first nine chapters describe central autonomic circuits from the cerebral cortex to the periphery. Eight additional chapters address specific bodily functions and their control by central autonomic circuits. Two additional chapters discuss cardio-respiratory integration and regulation of autonomic function by visceral and somatic afferents. All of the chapters are up-to-date and cover topics such as the central autonomic regulation of airways, gastrointestinal function, energy homeostasis, body temperature, and sexual function, reflecting the latest research.

This text is the second edition of this book. It expands the widely acclaimed 1981 book, filling more gaps between EEG and the physical sciences. EEG opens a “window on the mind” by finding new connections between psychology and physiology. Topics include synaptic sources, electrode placement, choice of reference, volume conduction, power and coherence, projection of scalp potentials to dura surface, dynamic signatures of conscious experience, and neural networks immersed in global fields of synaptic action.

One of the most fascinating developments in the field of neuroscience in the second half of the 20th century was the discovery of the endogenous capacity of the brain for reorganization during adult life. Morphological and functional mechanisms underlying brain plasticity have been extensively explored and characterized. However, our understanding of the functional significance of these plastic changes is still fragmentary. This book shows that brain plasticity plays an essential role in the regulation of hormonal levels. The second aim is to propose that hormones orchestrate the multiple endogenous plastic events of the brain for the generation of adequate physiological and behavioral responses in adaptation to and in prediction of changing life conditions. The book starts by introducing the conceptual backgrounds on the interactions of hormones and brain plasticity. It then devotes itself to the analysis of the role of brain plasticity in the regulation of the activity of endocrine glands. It examines different hormonal influences on brain plasticity. Then, it goes on to cover the interactions of hormones and brain plasticity along the life cycle under physiological and pathological conditions.

Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It looks at the co-evolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brains fundamental organizer of neuronal information. The small world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive metastable state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of cycles, this book travels from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage.

This book demonstrates how everything we put into our bodies effects certain neurotransmitters concerned with behavior and as a result has very direct consequences for how we think, feel, and act. The chapters introduce each of the main neurotransmitters involved with behavior, discuss its role in the brain, present some background on how it is generally turned on and off, and explain ways to influence it through what we consume. The book answers many questions, including: Why is eating chocolate so pleasurable? Can the function of just one small group of chemicals really determine whether you are happy or sad? Does marijuana help to improve your memory in old age? Is it really best to drink coffee if you want to wake up and be alert? Why is a drug like PCP potentially lethal? Why does drinking alcohol make you drowsy? Do cigarettes help to relieve anxiety? What should you consume if you are having trouble staying in your chair and focusing enough to get your work done? Why do treatments for the common cold make us drowsy? Can eating less food preserve your brain? What are the possible side effects of pills that claim to make you smarter? Why is it so hard to stop smoking? Why did witches once believe that they could fly?